publication
A paper on graphene surface stress biosensors has been published online.
2020/03/27 publication
A paper on graphene surface stress biosensors has been published online.
This paper is open access.
Title： A suspended graphene-based optical interferometric surface stress sensor for selective biomolecular detection
Autho： Shin Kidane, Hayato Ishida, Kazuaki Sawada and Kazuhiro Takahashi
Journal： Nanoscale Advances, Issue4, DOI: 10.1039/C9NA00788A
https://pubs.rsc.org/en/content/articlelanding/2020/na/c9na00788a
A paper on in-vivo sensors has been published in EurekAlert!
2020/03/07 publicationTopix
2020/3/7 A paper on in-vivo sensors has been published in EurekAlert!
It was also introduced in Medicalxpress and Bioengineer.
https://medicalxpress.com/news/2020-03-acids-bases-ph-brain.html
A paper on in-vivo sensors has been published by Nature Communications.
2020/02/06 InformationpublicationTopix
2020/2/6 A paper on in-vivo sensors has been published by Nature Communications. This work was supported by the Japan Science and Technology Agency (JST) under the Core Research for Evolutional Science and Technology (CREST) program.
- “CMOS-based bio-image sensor spatially resolves neural activity dependent proton dynamics in the living brain”
- 著者名：Hiroshi Horiuchi, Masakazu Agetsuma, Junko Ishida, Yusuke Nakamura, Dennis Lawrence Cheung, Shin Nanasaki, Yasuyuki Kimura, Tatsuya Iwata, Kazuhiro Takahashi, Kazuaki Sawada, Junichi Nabekura
- ＤＯＩ：10.1038/s41467-020-14571-y
◎We developed a thin CMOS ion image sensor that can be applied to living organisms, and succeeded in visualizing pH in the brain.We succeeded in visualizing pH in the brain by developing a thin CMOS ion image sensor that can be applied to living organisms.
◎We were able to detect dynamic changes in pH in the brain in response to visual stimuli.
| Abnormal pH (hydrogen ion concentration) has been observed in brain pathologies such as cerebral ischemia and epilepsy, and ultra-high resolution measurement of pH in the brain of living organisms may lead to the elucidation of new disease mechanisms and treatment methods. Hiroshi Horiuchi, Assistant Professor and Junichi Nabekura, Director of the Institute of Physiology, National Institutes of Natural Sciences, and Kazuaki Sawada, Professor of Toyohashi University of Technology, have developed a high-definition pH imaging tool that can be applied to living organisms. By visualizing brain pH in real time, they have succeeded for the first time in the world in capturing the dynamic changes in pH in the microenvironment as a result of neural activity. By applying this technique to future pathological research, it is expected to elucidate the mechanism of diseases.
The results of this research were published in the British scientific journal Nature Communications on February 5, 2020 (UK time). |
Academic paper written by Prof. Dr. Takahashi is released online
2019/02/28 publication
2019/2/28 Academic paper written by Prof. Dr. Takahashi is released online.
Author：Kazuhiro Takahashi, Toshinori Fujie, Reina Teramoto, Isao Takahashi, Nobutaka Sato, Shinji Takeoka, Kazuaki Sawada
Academic paper written by Ms. LEE is released online
2019/01/24 publication
2019/1/24 Academic paper written by Youna LEE is released online.
Title：High-density 2-μm-pitch pH image sensor with high-speed operation up to 1933 fps
Author：You-Na Lee*, Takeshi Araki, Yasuyuki Kimura, Fumihiro Dasai, Tatsuya Iwata, Kazuhiro Takahashi
